Biest 50:50 with Progesterone
Compounded Biest paired with progesterone for uterine protection.
Best for: Hot flashes · Night sweats · Sleep disruption · Mood
Free shipping · Cancel anytime · HSA / FSA eligible · No membership fee
Biest 50:50 combined with progesterone, for women with a uterus who choose a compounded estrogen approach. The progesterone protects the uterine lining when estrogen is used. The Biest component is compounded individually by a state-licensed 503A pharmacy rather than mass-manufactured to a standardized, tested product; we lead with body-identical options and do not claim a compounded plan is safer or more effective.
What it does
- Compounded Biest plus progesterone in one plan
- Progesterone included for uterine (endometrial) protection
- A personalization option chosen together with your clinician
The Biest component delivers estradiol and estriol to relieve estrogen-deficiency symptoms, while progesterone protects the uterine lining from the effects of estrogen. Because the estrogen component is compounded individually by a state-licensed 503A pharmacy rather than mass-manufactured to a standardized, tested product, this specific preparation is not reviewed for safety, efficacy, or dose consistency.
Your clinician prescribes the Biest strength and the progesterone dose, compounded by a licensed pharmacy and titrated to your symptoms.
Menopause is diagnosed and titrated by how you feel. Routine bloodwork is not required — your clinician may suggest tests in specific situations, but they are optional, not a prerequisite for care.
Ingredients
- Estradiol (compounded)
- Estriol (compounded)
- Progesterone
The price is the medication — the rest is included
- Free, discreet shipping
- Unlimited clinician messaging
- Automatic refills
- Cancel anytime — no lock-in
- No membership fee
- HSA / FSA eligible
What the guidelines support
The Menopause Society
For women with a uterus, a progestogen is added to estrogen to reduce the risk of endometrial hyperplasia and cancer.
ACOG
There is no evidence that compounded bioidentical hormones are safer or more effective than standard hormone therapy.
Where this fits in your care
Hot flashes & night sweats
Hot flashes and night sweats are the most common — and most treatable — symptoms of menopause. Hormone therapy is the most effective treatment available.
Sleep disruption
Menopause disrupts sleep through night sweats, anxiety, and falling progesterone. Treating the hormonal cause restores rest in a way sleep aids cannot.
Mood & brain fog
Brain fog, irritability, and low mood are real, hormone-driven symptoms of the menopause transition — not personal failings.
Other options to consider
Many women combine therapies. Your clinician helps you choose the right plan.
Estradiol patches
Transdermal patch, applied twice weekly · Prescription
$159/mo
monthly or quarterly billing
Estradiol patch, applied twice weekly.
Estradiol tablets
Oral tablet, once daily · Prescription
$79/mo
monthly or quarterly billing
Oral estradiol for menopause symptoms.
Estradiol gel
Transdermal gel, applied daily · Prescription
$99/mo
monthly or quarterly billing
Transdermal estradiol gel, applied daily.
Questions, answered
If you have a uterus, progesterone is added to estrogen to protect the uterine lining. Your clinician will confirm the right combination for you.
Important: compounded medication
The Biest component is a compounded medication. Compounded hormones, including estriol, are compounded individually by a state-licensed 503A pharmacy rather than mass-manufactured to a standardized, tested product. We do not claim this plan is safer, more natural, or more effective than standard hormone therapy. A licensed clinician determines whether it is appropriate for you.
Feel like yourself again.
Take the 3-minute assessment, then meet your clinician by video or phone. No obligation.